Details for gene set TGF-BETA RECEPTOR SIGNALING ACTIVATES SMADS%REACTOME%R-HSA-2173789.6[GSEA]

Table: GSEA Results Summary

Dataset	ranked_basal_vs_classical
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	TGF-BETA RECEPTOR SIGNALING ACTIVATES SMADS%REACTOME%R-HSA-2173789.6
Enrichment Score (ES)	0.7268879
Normalized Enrichment Score (NES)	2.065338
Nominal p-value	0.0
FDR q-value	0.0016455166
FWER p-Value	0.014

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	TGFB2	74	11.043	0.1159	Yes
2	ITGB6	96	10.078	0.2243	Yes
3	PMEPA1	299	6.262	0.2811	Yes
4	ITGB1	381	5.651	0.3380	Yes
5	STRAP	532	4.659	0.3803	Yes
6	TGFB1	563	4.495	0.4275	Yes
7	LTBP3	664	4.092	0.4664	Yes
8	ITGB5	703	3.937	0.5071	Yes
9	ITGAV	754	3.808	0.5457	Yes
10	ITGB8	827	3.602	0.5808	Yes
11	ITGB3	883	3.456	0.6153	Yes
12	SMURF2	918	3.383	0.6502	Yes
13	SMAD7	956	3.307	0.6841	Yes
14	LTBP2	1324	2.675	0.6928	Yes
15	PPP1CB	1519	2.353	0.7075	Yes
16	FKBP1A	1696	2.155	0.7212	Yes
17	XPO1	1968	1.912	0.7269	Yes
18	UBC	2489	1.548	0.7148	No
19	TGFB3	3235	1.168	0.6861	No
20	SMAD2	3332	1.127	0.6930	No
21	CBL	3426	1.091	0.6997	No
22	SMURF1	3464	1.078	0.7093	No
23	TGFBR2	3945	0.882	0.6922	No
24	NEDD8	4748	0.629	0.6545	No
25	PPP1CA	5476	0.464	0.6191	No
26	LTBP4	5820	0.392	0.6043	No
27	UCHL5	6208	0.322	0.5862	No
28	BAMBI	6456	0.282	0.5756	No
29	UBE2M	7077	0.197	0.5432	No
30	PPP1R15A	7323	0.167	0.5314	No
31	LTBP1	7816	0.107	0.5052	No
32	RPS27A	8359	0.056	0.4757	No
33	SMAD3	8566	0.037	0.4647	No
34	USP15	8970	-0.005	0.4423	No
35	TGFBR1	9072	-0.014	0.4368	No
36	MTMR4	9154	-0.023	0.4326	No
37	STUB1	9657	-0.070	0.4054	No
38	FURIN	10310	-0.151	0.3708	No
39	ITGA8	11039	-0.251	0.3331	No
40	SMAD4	12426	-0.507	0.2615	No
41	TGFBR3	12567	-0.539	0.2596	No
42	UBA52	12867	-0.609	0.2496	No
43	PPP1CC	13356	-0.729	0.2304	No
44	NEDD4L	14548	-1.151	0.1767	No
45	UBB	15321	-1.549	0.1506	No